Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

ABSTRACT Crimean-Congo hemorrhagic fever virus (CCHFV) infection can result in a severe hemorrhagic syndrome for which there are no antiviral interventions available to date. Certain RNA viruses, such as CCHFV, encode cysteine proteases of the ovarian tumor (OTU) family that antagonize interferon (I...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Florine E. M. Scholte, Brian L. Hua, Jessica R. Spengler, John V. Dzimianski, JoAnn D. Coleman-McCray, Stephen R. Welch, Laura K. McMullan, Stuart T. Nichol, Scott D. Pegan, Christina F. Spiropoulou, Éric Bergeron
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Nairoviridae
RNA replication
antiviral agents
bunyavirus
innate immunity
interferon-stimulated gene-15
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/640e7af79e2e4deb96661b33a8af2153
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/640e7af79e2e4deb96661b33a8af2153

Ejemplares similares