Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

ABSTRACT Crimean-Congo hemorrhagic fever virus (CCHFV) infection can result in a severe hemorrhagic syndrome for which there are no antiviral interventions available to date. Certain RNA viruses, such as CCHFV, encode cysteine proteases of the ovarian tumor (OTU) family that antagonize interferon (I...

Full description

Saved in:
Bibliographic Details
Main Authors: Florine E. M. Scholte, Brian L. Hua, Jessica R. Spengler, John V. Dzimianski, JoAnn D. Coleman-McCray, Stephen R. Welch, Laura K. McMullan, Stuart T. Nichol, Scott D. Pegan, Christina F. Spiropoulou, Éric Bergeron
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
Nairoviridae
RNA replication
antiviral agents
bunyavirus
innate immunity
interferon-stimulated gene-15
Microbiology
QR1-502
Online Access:https://doaj.org/article/640e7af79e2e4deb96661b33a8af2153
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/640e7af79e2e4deb96661b33a8af2153

Similar Items