Functional characteristics of the naked mole rat μ-opioid receptor.

While humans and most animals respond to µ-opioid receptor (MOR) agonists with analgesia and decreased aggression, in the naked mole rat (NMR) opioids induce hyperalgesia and severe aggression. Single nucleotide polymorphisms in the human mu-opioid receptor gene (OPRM1) can underlie altered behavior...

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Autores principales: Melanie Busch-Dienstfertig, Clarisse A Roth, Christoph Stein
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/641437eb37c945e2a1e871e5de2bb1fd
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