Functional characteristics of the naked mole rat μ-opioid receptor.
While humans and most animals respond to µ-opioid receptor (MOR) agonists with analgesia and decreased aggression, in the naked mole rat (NMR) opioids induce hyperalgesia and severe aggression. Single nucleotide polymorphisms in the human mu-opioid receptor gene (OPRM1) can underlie altered behavior...
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Autores principales: | Melanie Busch-Dienstfertig, Clarisse A Roth, Christoph Stein |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/641437eb37c945e2a1e871e5de2bb1fd |
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