Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin

Centromeres are a self-propagating chromatin structure that feature nucleosomes containing histone H3 variant CENP-A. Here, the authors screen for factors that play a role in CENP-A chromatin maintenance, finding that SUMO-protease SENP6 controls inheritance of chromatin bound CENP-A and is required...

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Autores principales: Sreyoshi Mitra, Dani L. Bodor, Ana F. David, Izma Abdul-Zani, João F. Mata, Beate Neumann, Sabine Reither, Christian Tischer, Lars E. T. Jansen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/641a9f1477b540ab8b0adfe5757d8257
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