Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin

Centromeres are a self-propagating chromatin structure that feature nucleosomes containing histone H3 variant CENP-A. Here, the authors screen for factors that play a role in CENP-A chromatin maintenance, finding that SUMO-protease SENP6 controls inheritance of chromatin bound CENP-A and is required...

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Autores principales:	Sreyoshi Mitra, Dani L. Bodor, Ana F. David, Izma Abdul-Zani, João F. Mata, Beate Neumann, Sabine Reither, Christian Tischer, Lars E. T. Jansen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/641a9f1477b540ab8b0adfe5757d8257
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id	oai:doaj.org-article:641a9f1477b540ab8b0adfe5757d8257
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spelling	oai:doaj.org-article:641a9f1477b540ab8b0adfe5757d82572021-12-02T17:33:15ZGenetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin10.1038/s41467-019-14276-x2041-1723https://doaj.org/article/641a9f1477b540ab8b0adfe5757d82572020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14276-xhttps://doaj.org/toc/2041-1723Centromeres are a self-propagating chromatin structure that feature nucleosomes containing histone H3 variant CENP-A. Here, the authors screen for factors that play a role in CENP-A chromatin maintenance, finding that SUMO-protease SENP6 controls inheritance of chromatin bound CENP-A and is required for the maintenance of the centromere and kinetochore complex.Sreyoshi MitraDani L. BodorAna F. DavidIzma Abdul-ZaniJoão F. MataBeate NeumannSabine ReitherChristian TischerLars E. T. JansenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sreyoshi Mitra Dani L. Bodor Ana F. David Izma Abdul-Zani João F. Mata Beate Neumann Sabine Reither Christian Tischer Lars E. T. Jansen Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin
description	Centromeres are a self-propagating chromatin structure that feature nucleosomes containing histone H3 variant CENP-A. Here, the authors screen for factors that play a role in CENP-A chromatin maintenance, finding that SUMO-protease SENP6 controls inheritance of chromatin bound CENP-A and is required for the maintenance of the centromere and kinetochore complex.
format	article
author	Sreyoshi Mitra Dani L. Bodor Ana F. David Izma Abdul-Zani João F. Mata Beate Neumann Sabine Reither Christian Tischer Lars E. T. Jansen
author_facet	Sreyoshi Mitra Dani L. Bodor Ana F. David Izma Abdul-Zani João F. Mata Beate Neumann Sabine Reither Christian Tischer Lars E. T. Jansen
author_sort	Sreyoshi Mitra
title	Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin
title_short	Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin
title_full	Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin
title_fullStr	Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin
title_full_unstemmed	Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin
title_sort	genetic screening identifies a sumo protease dynamically maintaining centromeric chromatin
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/641a9f1477b540ab8b0adfe5757d8257
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Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin

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