Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin
Centromeres are a self-propagating chromatin structure that feature nucleosomes containing histone H3 variant CENP-A. Here, the authors screen for factors that play a role in CENP-A chromatin maintenance, finding that SUMO-protease SENP6 controls inheritance of chromatin bound CENP-A and is required...
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Autores principales: | Sreyoshi Mitra, Dani L. Bodor, Ana F. David, Izma Abdul-Zani, João F. Mata, Beate Neumann, Sabine Reither, Christian Tischer, Lars E. T. Jansen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/641a9f1477b540ab8b0adfe5757d8257 |
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