Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood
Abstract Corline Heparin Conjugate (CHC), a compound of multiple unfractionated heparin chains, coats cells with a glycocalyx-like layer and may inhibit (xeno)transplant-associated activation of the plasma cascade systems. Here, we investigated the use of CHC to protect WT and genetically modified (...
Saved in:
Main Authors: | Anjan K. Bongoni, Evelyn Salvaris, Sofia Nordling, Nikolai Klymiuk, Eckhard Wolf, David L. Ayares, Robert Rieben, Peetra U. Magnusson, Peter J. Cowan |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/644500d90d4649d2a075e77455a6fe32 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Anticancer Effect of Heparin–Taurocholate Conjugate on Orthotopically Induced Exocrine and Endocrine Pancreatic Cancer
by: Hae Hyun Hwang, et al.
Published: (2021) -
A potent truncated form of human soluble CR1 is protective in a mouse model of renal ischemia–reperfusion injury
by: Anjan K. Bongoni, et al.
Published: (2021) -
Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft
by: Muhammad M. Mohiuddin, et al.
Published: (2016) -
Preparation and characterization of self-assembled nanoparticles based on low-molecular-weight heparin and stearylamine conjugates for controlled delivery of docetaxel
by: Kim DH, et al.
Published: (2014) -
Surface modification of endovascular stents with rosuvastatin and heparin-loaded biodegradable nanofibers by electrospinning
by: Janjic M, et al.
Published: (2017)