Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling

NMDA receptor-dependent long-term depression (NMDAR-LTD) is a form of synaptic plasticity mediated by reduced recycling of AMPA receptors to the plasma membrane. Here the authors show that autophagy is a regulator of this endocytic recycling and autophagy upregulation dampens NMDAR-LTD in adulthood.

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Auteurs principaux: Hongmei Shen, Huiwen Zhu, Debabrata Panja, Qinhua Gu, Zheng Li
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/645e3ddba88342fa8b8a5bfcca5bc4bf
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