Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling

NMDA receptor-dependent long-term depression (NMDAR-LTD) is a form of synaptic plasticity mediated by reduced recycling of AMPA receptors to the plasma membrane. Here the authors show that autophagy is a regulator of this endocytic recycling and autophagy upregulation dampens NMDAR-LTD in adulthood.

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Autores principales:	Hongmei Shen, Huiwen Zhu, Debabrata Panja, Qinhua Gu, Zheng Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/645e3ddba88342fa8b8a5bfcca5bc4bf
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spelling	oai:doaj.org-article:645e3ddba88342fa8b8a5bfcca5bc4bf2021-12-02T17:52:20ZAutophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling10.1038/s41467-020-16794-52041-1723https://doaj.org/article/645e3ddba88342fa8b8a5bfcca5bc4bf2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16794-5https://doaj.org/toc/2041-1723NMDA receptor-dependent long-term depression (NMDAR-LTD) is a form of synaptic plasticity mediated by reduced recycling of AMPA receptors to the plasma membrane. Here the authors show that autophagy is a regulator of this endocytic recycling and autophagy upregulation dampens NMDAR-LTD in adulthood.Hongmei ShenHuiwen ZhuDebabrata PanjaQinhua GuZheng LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hongmei Shen Huiwen Zhu Debabrata Panja Qinhua Gu Zheng Li Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
description	NMDA receptor-dependent long-term depression (NMDAR-LTD) is a form of synaptic plasticity mediated by reduced recycling of AMPA receptors to the plasma membrane. Here the authors show that autophagy is a regulator of this endocytic recycling and autophagy upregulation dampens NMDAR-LTD in adulthood.
format	article
author	Hongmei Shen Huiwen Zhu Debabrata Panja Qinhua Gu Zheng Li
author_facet	Hongmei Shen Huiwen Zhu Debabrata Panja Qinhua Gu Zheng Li
author_sort	Hongmei Shen
title	Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
title_short	Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
title_full	Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
title_fullStr	Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
title_full_unstemmed	Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
title_sort	autophagy controls the induction and developmental decline of nmdar-ltd through endocytic recycling
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/645e3ddba88342fa8b8a5bfcca5bc4bf
work_keys_str_mv	AT hongmeishen autophagycontrolstheinductionanddevelopmentaldeclineofnmdarltdthroughendocyticrecycling AT huiwenzhu autophagycontrolstheinductionanddevelopmentaldeclineofnmdarltdthroughendocyticrecycling AT debabratapanja autophagycontrolstheinductionanddevelopmentaldeclineofnmdarltdthroughendocyticrecycling AT qinhuagu autophagycontrolstheinductionanddevelopmentaldeclineofnmdarltdthroughendocyticrecycling AT zhengli autophagycontrolstheinductionanddevelopmentaldeclineofnmdarltdthroughendocyticrecycling
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Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling

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