GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson disease

Cholinergic interneurons of the striatum are involved reward-related behaviors and have been implicated in Parkinson’s disease. Here the authors report that half of cholinergic neurons co-release acetylcholine and GABA, and study the role of these neurons in a model of Parkinson’s Disease.

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Autores principales: N. Lozovaya, S. Eftekhari, R. Cloarec, L. A. Gouty-Colomer, A. Dufour, B. Riffault, M. Billon-Grand, A. Pons-Bennaceur, N. Oumar, N. Burnashev, Y. Ben-Ari, C. Hammond
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6462473cc62646758946f586af2ca644
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