Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden
Germline variants that affect the expression or function of protein-coding regions of cancer genes are associated with cancer susceptibility. Here, the authors show that a larger number of germline variants are present in early-onset cancers, while acquired somatic mutations are prevalent in cancers...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/6465db3a292f40d4a8d14f8e7096e431 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|