Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice

Heterogeneous nuclear ribonucleoproteins (hnRNPs) play critical roles in the biogenesis, localization and transport of RNA. Here authors investigate a role for hnRNPs in sterol metabolism in mice and provide insights into their role in selective promoter activation.

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Autores principales: Zhengyi Zhang, An-Chieh Feng, David Salisbury, Xin Liu, Xiaohui Wu, Jason Kim, Irina Lapina, Dan Wang, Brennan Lee, Josue Fraga, Calvin Pan, Kevin J. Williams, Aldons J. Lusis, Phil Scumpia, Tamer Sallam
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/646bf0de5fae4234ab6ca6f891819503
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spelling oai:doaj.org-article:646bf0de5fae4234ab6ca6f8918195032021-12-02T17:31:41ZCollaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice10.1038/s41467-020-14711-42041-1723https://doaj.org/article/646bf0de5fae4234ab6ca6f8918195032020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14711-4https://doaj.org/toc/2041-1723Heterogeneous nuclear ribonucleoproteins (hnRNPs) play critical roles in the biogenesis, localization and transport of RNA. Here authors investigate a role for hnRNPs in sterol metabolism in mice and provide insights into their role in selective promoter activation.Zhengyi ZhangAn-Chieh FengDavid SalisburyXin LiuXiaohui WuJason KimIrina LapinaDan WangBrennan LeeJosue FragaCalvin PanKevin J. WilliamsAldons J. LusisPhil ScumpiaTamer SallamNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhengyi Zhang
An-Chieh Feng
David Salisbury
Xin Liu
Xiaohui Wu
Jason Kim
Irina Lapina
Dan Wang
Brennan Lee
Josue Fraga
Calvin Pan
Kevin J. Williams
Aldons J. Lusis
Phil Scumpia
Tamer Sallam
Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
description Heterogeneous nuclear ribonucleoproteins (hnRNPs) play critical roles in the biogenesis, localization and transport of RNA. Here authors investigate a role for hnRNPs in sterol metabolism in mice and provide insights into their role in selective promoter activation.
format article
author Zhengyi Zhang
An-Chieh Feng
David Salisbury
Xin Liu
Xiaohui Wu
Jason Kim
Irina Lapina
Dan Wang
Brennan Lee
Josue Fraga
Calvin Pan
Kevin J. Williams
Aldons J. Lusis
Phil Scumpia
Tamer Sallam
author_facet Zhengyi Zhang
An-Chieh Feng
David Salisbury
Xin Liu
Xiaohui Wu
Jason Kim
Irina Lapina
Dan Wang
Brennan Lee
Josue Fraga
Calvin Pan
Kevin J. Williams
Aldons J. Lusis
Phil Scumpia
Tamer Sallam
author_sort Zhengyi Zhang
title Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
title_short Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
title_full Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
title_fullStr Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
title_full_unstemmed Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
title_sort collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/646bf0de5fae4234ab6ca6f891819503
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