Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide

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Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide

How DNA polymerases discriminate against oxidized and undamaged nucleotides during DNA repair is not fully understood. Here, the authors reveal high-resolution timelapse X-ray crystallography snapshots of DSB repair polymerase μ undergoing DNA synthesis providing mechanistic insights into the proces...

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Autores principales:	Joonas A. Jamsen, Akira Sassa, David D. Shock, William A. Beard, Samuel H. Wilson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/64968d1c0b29445aac6abe67bd0ccdd1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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