The Fungal Quorum-Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity

ABSTRACT Farnesol, produced by the polymorphic fungus Candida albicans, is the first quorum-sensing molecule discovered in eukaryotes. Its main function is control of C. albicans filamentation, a process closely linked to pathogenesis. In this study, we analyzed the effects of farnesol on innate imm...

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Autores principales: Ines Leonhardt, Steffi Spielberg, Michael Weber, Daniela Albrecht-Eckardt, Markus Bläss, Ralf Claus, Dagmar Barz, Kirstin Scherlach, Christian Hertweck, Jürgen Löffler, Kerstin Hünniger, Oliver Kurzai
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Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/6497b293fb4646f19f117bfd66ba9845
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