The synaptic receptor Lrp4 promotes peripheral nerve regeneration

Axons of the peripheral nervous system regenerate along Schwann cells following injury. Here, the authors show that regenerating axons follow pioneer axons and this process is mediated by lipoprotein receptor-related protein 4 (Lrp4), a protein otherwise known for its role in synapse formation.

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Auteurs principaux: Katherine D. Gribble, Lauren J. Walker, Louis Saint-Amant, John Y. Kuwada, Michael Granato
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/64b3962177964d1280be358fae515cc7
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