Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis.
The rise of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis around the world, including in industrialized nations, poses a great threat to human health and defines a need to develop new, effective and inexpensive anti-tubercular agents. Previously we developed a chemical...
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Main Authors: | Sarah L Kinnings, Nina Liu, Nancy Buchmeier, Peter J Tonge, Lei Xie, Philip E Bourne |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2009
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Online Access: | https://doaj.org/article/64c00c83b6504f478fcb12e42c5a243c |
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