Development of Natural Polysaccharide–Based Nanoparticles of Berberine to Enhance Oral Bioavailability: Formulation, Optimization, Ex Vivo, and In Vivo Assessment

The phytogenous alkaloid berberine (BBR) has become a potential drug for the treatment of diabetes, hyperlipidemia, and cancer. However, its therapeutic potential is limited because ofpoor intestinal absorption due to its efflux by the <i>P</i>-gp expressed in the intestinal lumen. There...

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Autores principales: Kanchan Kohli, Ali Mujtaba, Rozina Malik, Saima Amin, Md Sarfaraz Alam, Abuzer Ali, Md. Abul Barkat, Mohammad Javed Ansari
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/64cd336841514d73afa1fff816bbab57
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