Development of Natural Polysaccharide–Based Nanoparticles of Berberine to Enhance Oral Bioavailability: Formulation, Optimization, Ex Vivo, and In Vivo Assessment
The phytogenous alkaloid berberine (BBR) has become a potential drug for the treatment of diabetes, hyperlipidemia, and cancer. However, its therapeutic potential is limited because ofpoor intestinal absorption due to its efflux by the <i>P</i>-gp expressed in the intestinal lumen. There...
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Format: | article |
Langue: | EN |
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MDPI AG
2021
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Accès en ligne: | https://doaj.org/article/64cd336841514d73afa1fff816bbab57 |
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