Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion

The mechanisms linking phenotypic heterogeneity to collective cancer invasion are unclear. Here the authors develop an image-guided genomic technique to select and amplify leader and follower cells fromin vitroinvading cell packs and find a cooperative symbiotic relationship between these two cell p...

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Autores principales: J. Konen, E. Summerbell, B. Dwivedi, K. Galior, Y. Hou, L. Rusnak, A. Chen, J. Saltz, W. Zhou, L. H. Boise, P. Vertino, L. Cooper, K. Salaita, J. Kowalski, A. I. Marcus
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/64f60da8ca2d4bdfb02d02820683558f
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