Effect of adjuvants on responses to skin immunization by microneedles coated with influenza subunit vaccine.

Recent studies have demonstrated the effectiveness of vaccine delivery to the skin by vaccine-coated microneedles; however there is little information on the effects of adjuvants using this approach for vaccination. Here we investigate the use of TLR ligands as adjuvants with skin-based delivery of...

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Autores principales: William C Weldon, Vladimir G Zarnitsyn, E Stein Esser, Misha T Taherbhai, Dimitrios G Koutsonanos, Elena V Vassilieva, Ioanna Skountzou, Mark R Prausnitz, Richard W Compans
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/64fbf7d8229249eeb0167bf3d49491d8
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