Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Infection <italic toggle="yes">In Vivo</italic> by a Mechanism Dependent on T Lymphocytes
ABSTRACT Heme oxygenase-1 (HO-1) is a stress response antioxidant enzyme which catalyzes the degradation of heme released during inflammation. HO-1 expression is upregulated in both experimental and human Mycobacterium tuberculosis infection, and in patients it is a biomarker of active disease. Whet...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/64fdecdf902b4fefb96dcde0a01ffc15 |
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