Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals

Assigning inter-individual similarities to genetic and non-genetic factors is central to quantitative genetics. Here, the authors look at phenotypic covariance among pairs of individuals for 32 traits across the UK Biobank, from nominally unrelated pairs through to monozygotic twins.

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Detalles Bibliográficos
Autores principales: Kathryn E. Kemper, Loic Yengo, Zhili Zheng, Abdel Abdellaoui, Matthew C. Keller, Michael E. Goddard, Naomi R. Wray, Jian Yang, Peter M. Visscher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/64fff80d790b43149c2e74f5578376c3
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Sumario:Assigning inter-individual similarities to genetic and non-genetic factors is central to quantitative genetics. Here, the authors look at phenotypic covariance among pairs of individuals for 32 traits across the UK Biobank, from nominally unrelated pairs through to monozygotic twins.