Causes and Effects of Loss of Classical Nonhomologous End Joining Pathway in Parasitic Eukaryotes

ABSTRACT We report frequent losses of components of the classical nonhomologous end joining pathway (C-NHEJ), one of the main eukaryotic tools for end joining repair of DNA double-strand breaks, in several lineages of parasitic protists. Moreover, we have identified a single lineage among trypanosom...

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Autores principales: Anna Nenarokova, Kristína Záhonová, Marija Krasilnikova, Ondřej Gahura, Richard McCulloch, Alena Zíková, Vyacheslav Yurchenko, Julius Lukeš
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/654d7dbb7b3644f2bb0e34c89954906e
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