Self-organization of Plk4 regulates symmetry breaking in centriole duplication
During centriole duplication, Plk4 regulates formation of a single daughter centriole adjacent to the mother centriole, but the mechanism is unclear. Here, the authors show that Plk4 can undergo liquid–liquid phase separation and that the condensation properties are regulated by autophosphorylation....
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| Auteurs principaux: | , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2019
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| Accès en ligne: | https://doaj.org/article/655ee060eb5d42cabcf5c08792cc7305 |
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