GIANA allows computationally-efficient TCR clustering and multi-disease repertoire classification by isometric transformation

Grouping T-cell receptors (TCRs) by sequence similarity could lead to new immunological insights. Here, the authors propose a tool that allows the rapid clustering of millions of TCR sequences, identifying TCRs potentially associated with the response to cancer, infectious and autoimmune diseases.

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Detalles Bibliográficos
Autores principales: Hongyi Zhang, Xiaowei Zhan, Bo Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/6567862dd2b246dca27592acd4fee3c0
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