Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity

Abstract Cellular heterogeneity in cancer represents a significant challenge. In order to develop effective and lasting therapies, it is essential to understand the source of this heterogeneity, and its role in tumor progression and therapy resistance. Here, we consider not only genetic and epigenet...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Geoffrey M. Wahl, Benjamin T. Spike
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Accès en ligne:https://doaj.org/article/657a1343dbc640d09e0f4e77d11190cc
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!