Minor groove binder distamycin remodels chromatin but inhibits transcription.

The condensed structure of chromatin limits access of cellular machinery towards template DNA. This in turn represses essential processes like transcription, replication, repair and recombination. The repression is alleviated by a variety of energy dependent processes, collectively known as "ch...

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Autores principales: Parijat Majumder, Amrita Banerjee, Jayasha Shandilya, Parijat Senapati, Snehajyoti Chatterjee, Tapas K Kundu, Dipak Dasgupta
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/65891f43981448aaae46fff8dee0b8a7
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