Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore

Chromosomes bind microtubules (MT) from opposite spindle poles and the generated tension stabilizes kinetochore-MT attachments. Here the authors measure kinetochore forces by engineering two force sensors and propose that kinetochore fibers exert hundreds of pNs of force to bioriented kinetochores.

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Detalles Bibliográficos
Autores principales: Anna A. Ye, Stuart Cane, Thomas J. Maresca
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Q
Acceso en línea:https://doaj.org/article/65caf202ae7448c48eaf1423297ed30a
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