Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore

Chromosomes bind microtubules (MT) from opposite spindle poles and the generated tension stabilizes kinetochore-MT attachments. Here the authors measure kinetochore forces by engineering two force sensors and propose that kinetochore fibers exert hundreds of pNs of force to bioriented kinetochores.

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Auteurs principaux: Anna A. Ye, Stuart Cane, Thomas J. Maresca
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/65caf202ae7448c48eaf1423297ed30a
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