Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore

Chromosomes bind microtubules (MT) from opposite spindle poles and the generated tension stabilizes kinetochore-MT attachments. Here the authors measure kinetochore forces by engineering two force sensors and propose that kinetochore fibers exert hundreds of pNs of force to bioriented kinetochores.

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Autores principales:	Anna A. Ye, Stuart Cane, Thomas J. Maresca
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/65caf202ae7448c48eaf1423297ed30a
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spelling	oai:doaj.org-article:65caf202ae7448c48eaf1423297ed30a2021-12-02T17:32:36ZChromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore10.1038/ncomms132212041-1723https://doaj.org/article/65caf202ae7448c48eaf1423297ed30a2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13221https://doaj.org/toc/2041-1723Chromosomes bind microtubules (MT) from opposite spindle poles and the generated tension stabilizes kinetochore-MT attachments. Here the authors measure kinetochore forces by engineering two force sensors and propose that kinetochore fibers exert hundreds of pNs of force to bioriented kinetochores.Anna A. YeStuart CaneThomas J. MarescaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anna A. Ye Stuart Cane Thomas J. Maresca Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore
description	Chromosomes bind microtubules (MT) from opposite spindle poles and the generated tension stabilizes kinetochore-MT attachments. Here the authors measure kinetochore forces by engineering two force sensors and propose that kinetochore fibers exert hundreds of pNs of force to bioriented kinetochores.
format	article
author	Anna A. Ye Stuart Cane Thomas J. Maresca
author_facet	Anna A. Ye Stuart Cane Thomas J. Maresca
author_sort	Anna A. Ye
title	Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore
title_short	Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore
title_full	Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore
title_fullStr	Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore
title_full_unstemmed	Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore
title_sort	chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/65caf202ae7448c48eaf1423297ed30a
work_keys_str_mv	AT annaaye chromosomebiorientationproduceshundredsofpiconewtonsatametazoankinetochore AT stuartcane chromosomebiorientationproduceshundredsofpiconewtonsatametazoankinetochore AT thomasjmaresca chromosomebiorientationproduceshundredsofpiconewtonsatametazoankinetochore
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Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore

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