Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes

ABSTRACT West Nile virus (WNV) is an emerging neuroinvasive flavivirus that now causes significant morbidity and mortality worldwide. The innate and adaptive immune responses to WNV infection have been well studied in C57BL/6J inbred mice, but this model lacks the variations in susceptibility, immun...

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Autores principales: Jessica B. Graham, Sunil Thomas, Jessica Swarts, Aimee A. McMillan, Martin T. Ferris, Mehul S. Suthar, Piper M. Treuting, Renee Ireton, Michael Gale, Jennifer M. Lund
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/65d31289859044929ba15da991eaaa1b
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