Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes
ABSTRACT West Nile virus (WNV) is an emerging neuroinvasive flavivirus that now causes significant morbidity and mortality worldwide. The innate and adaptive immune responses to WNV infection have been well studied in C57BL/6J inbred mice, but this model lacks the variations in susceptibility, immun...
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Autores principales: | Jessica B. Graham, Sunil Thomas, Jessica Swarts, Aimee A. McMillan, Martin T. Ferris, Mehul S. Suthar, Piper M. Treuting, Renee Ireton, Michael Gale, Jennifer M. Lund |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://doaj.org/article/65d31289859044929ba15da991eaaa1b |
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