Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway

Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. The high mortality associated with this malignancy indicates the need for new therapeutic interventions with fewer side effects. Natural comp...

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Autores principales: Kirti.S. Prabhu, Ajaz A. Bhat, Kodappully S. Siveen, Shilpa Kuttikrishnan, Syed Shadab Raza, Thesni Raheed, Anh Jochebeth, Abdul Q. Khan, M.Zafar Chawdhery, Mohammad Haris, Michal Kulinski, Said Dermime, Martin Steinhoff, Shahab Uddin
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Apoptosis
Antiproliferative
Alkaloids
Antioxidants
Cancer stem cells
Sanguinarine
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/65d7433946d144e296f1d326094998de
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https://doaj.org/article/65d7433946d144e296f1d326094998de

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