FEDS: a Novel Fluorescence-Based High-Throughput Method for Measuring DNA Supercoiling <italic toggle="yes">In Vivo</italic>

ABSTRACT DNA supercoiling (DS) is essential for life because it controls critical processes, including transcription, replication, and recombination. Current methods to measure DNA supercoiling in vivo are laborious and unable to examine single cells. Here, we report a method for high-throughput mea...

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Autores principales: Alexandre Duprey, Eduardo A. Groisman
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/65db34ab76d84080becb993baa6e4e72
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