CD63<sup>+</sup> and MHC Class I<sup>+</sup> Subsets of Extracellular Vesicles Produced by Wild-Type and CD47-Deficient Jurkat T Cells Have Divergent Functional Effects on Endothelial Cell Gene Expression

CD63<sup>+</sup> and MHC Class I<sup>+</sup> Subsets of Extracellular Vesicles Produced by Wild-Type and CD47-Deficient Jurkat T Cells Have Divergent Functional Effects on Endothelial Cell Gene Expression

T cells and endothelial cells engage in bidirectional communication that regulates angiogenesis and T cell transmigration. Extracellular vesicles (EVs) mediate intercellular communication by the transfer of bioactive molecules including RNAs. EVs produced by a given cell type are heterogeneous in th...

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Bibliographic Details
Main Authors: Sukhbir Kaur, Abdel G. Elkahloun, Jennifer D. Petersen, Anush Arakelyan, Ferenc Livak, Satya P. Singh, Leonid Margolis, Joshua Zimmerberg, David D. Roberts
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
extracellular vesicles
non-coding RNAs
cell-cell communication
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/65dcaa0b024640f7ab18112353ea5d40
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