The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration.

The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration.

Rhodopsin mistrafficking can cause photoreceptor (PR) degeneration. Upon light exposure, activated rhodopsin 1 (Rh1) in Drosophila PRs is internalized via endocytosis and degraded in lysosomes. Whether internalized Rh1 can be recycled is unknown. Here, we show that the retromer complex is expressed...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Shiuan Wang, Kai Li Tan, Melina A Agosto, Bo Xiong, Shinya Yamamoto, Hector Sandoval, Manish Jaiswal, Vafa Bayat, Ke Zhang, Wu-Lin Charng, Gabriela David, Lita Duraine, Kartik Venkatachalam, Theodore G Wensel, Hugo J Bellen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/65e1429ffb374718abe3785f3e9b39d5
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares