Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity

Centriolar separation is thought to be crucial for centriole duplication, but the mechanism behind separation is poorly understood. Here, using micropatterning, the authors report that actomyosin forces influence the direction, distance, and time of centriole separation.

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Autores principales:	Elisa Vitiello, Philippe Moreau, Vanessa Nunes, Amel Mettouchi, Helder Maiato, Jorge G. Ferreira, Irène Wang, Martial Balland
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/65e5c4e2368645a7ad2f6b3e546366e0
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spelling	oai:doaj.org-article:65e5c4e2368645a7ad2f6b3e546366e02021-12-02T16:58:24ZActo-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity10.1038/s41467-018-07965-62041-1723https://doaj.org/article/65e5c4e2368645a7ad2f6b3e546366e02019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07965-6https://doaj.org/toc/2041-1723Centriolar separation is thought to be crucial for centriole duplication, but the mechanism behind separation is poorly understood. Here, using micropatterning, the authors report that actomyosin forces influence the direction, distance, and time of centriole separation.Elisa VitielloPhilippe MoreauVanessa NunesAmel MettouchiHelder MaiatoJorge G. FerreiraIrène WangMartial BallandNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elisa Vitiello Philippe Moreau Vanessa Nunes Amel Mettouchi Helder Maiato Jorge G. Ferreira Irène Wang Martial Balland Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
description	Centriolar separation is thought to be crucial for centriole duplication, but the mechanism behind separation is poorly understood. Here, using micropatterning, the authors report that actomyosin forces influence the direction, distance, and time of centriole separation.
format	article
author	Elisa Vitiello Philippe Moreau Vanessa Nunes Amel Mettouchi Helder Maiato Jorge G. Ferreira Irène Wang Martial Balland
author_facet	Elisa Vitiello Philippe Moreau Vanessa Nunes Amel Mettouchi Helder Maiato Jorge G. Ferreira Irène Wang Martial Balland
author_sort	Elisa Vitiello
title	Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
title_short	Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
title_full	Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
title_fullStr	Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
title_full_unstemmed	Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
title_sort	acto-myosin force organization modulates centriole separation and plk4 recruitment to ensure centriole fidelity
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/65e5c4e2368645a7ad2f6b3e546366e0
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Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity

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