Establishment of a Rapid Detection System for ISG20-Dependent SARS-CoV-2 Subreplicon RNA Degradation Induced by Interferon-α

Inhaled nebulized interferon (IFN)-α and IFN-β have been shown to be effective in the management of coronavirus disease 2019 (COVID-19). We aimed to construct a virus-free rapid detection system for high-throughput screening of IFN-like compounds that induce viral RNA degradation and suppress the re...

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Autores principales: Yutaka Furutani, Mariko Toguchi, Shoko Higuchi, Kaori Yanaka, Luc Gailhouste, Xian-Yang Qin, Takahiro Masaki, Sae Ochi, Tomokazu Matsuura
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/66259d5985bd428b9b4e9acf53472578
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