A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion

Adipocyte progenitor cells (APCs) are found tethered to adipose tissue blood vessel walls and can differentiate into adipocytes. Here the authors show that PPARγ controls angiogenesis by stimulating APC–blood vessel interaction and retention via a transcriptional network that includes PDGFRβand VEGF...

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Autores principales: Yuwei Jiang, Daniel C. Berry, Ayoung Jo, Wei Tang, Robert W. Arpke, Michael Kyba, Jonathan M. Graff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/6640abda09f447389e85d6e9e242c618
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