A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion

Adipocyte progenitor cells (APCs) are found tethered to adipose tissue blood vessel walls and can differentiate into adipocytes. Here the authors show that PPARγ controls angiogenesis by stimulating APC–blood vessel interaction and retention via a transcriptional network that includes PDGFRβand VEGF...

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Autores principales:	Yuwei Jiang, Daniel C. Berry, Ayoung Jo, Wei Tang, Robert W. Arpke, Michael Kyba, Jonathan M. Graff
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6640abda09f447389e85d6e9e242c618
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id	oai:doaj.org-article:6640abda09f447389e85d6e9e242c618
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spelling	oai:doaj.org-article:6640abda09f447389e85d6e9e242c6182021-12-02T14:42:43ZA PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion10.1038/ncomms159262041-1723https://doaj.org/article/6640abda09f447389e85d6e9e242c6182017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15926https://doaj.org/toc/2041-1723Adipocyte progenitor cells (APCs) are found tethered to adipose tissue blood vessel walls and can differentiate into adipocytes. Here the authors show that PPARγ controls angiogenesis by stimulating APC–blood vessel interaction and retention via a transcriptional network that includes PDGFRβand VEGF.Yuwei JiangDaniel C. BerryAyoung JoWei TangRobert W. ArpkeMichael KybaJonathan M. GraffNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuwei Jiang Daniel C. Berry Ayoung Jo Wei Tang Robert W. Arpke Michael Kyba Jonathan M. Graff A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion
description	Adipocyte progenitor cells (APCs) are found tethered to adipose tissue blood vessel walls and can differentiate into adipocytes. Here the authors show that PPARγ controls angiogenesis by stimulating APC–blood vessel interaction and retention via a transcriptional network that includes PDGFRβand VEGF.
format	article
author	Yuwei Jiang Daniel C. Berry Ayoung Jo Wei Tang Robert W. Arpke Michael Kyba Jonathan M. Graff
author_facet	Yuwei Jiang Daniel C. Berry Ayoung Jo Wei Tang Robert W. Arpke Michael Kyba Jonathan M. Graff
author_sort	Yuwei Jiang
title	A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion
title_short	A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion
title_full	A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion
title_fullStr	A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion
title_full_unstemmed	A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion
title_sort	pparγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6640abda09f447389e85d6e9e242c618
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A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion

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