A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion

Adipocyte progenitor cells (APCs) are found tethered to adipose tissue blood vessel walls and can differentiate into adipocytes. Here the authors show that PPARγ controls angiogenesis by stimulating APC–blood vessel interaction and retention via a transcriptional network that includes PDGFRβand VEGF...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuwei Jiang, Daniel C. Berry, Ayoung Jo, Wei Tang, Robert W. Arpke, Michael Kyba, Jonathan M. Graff
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/6640abda09f447389e85d6e9e242c618
Tags: Add Tag
No Tags, Be the first to tag this record!