Deletion of TLR4 reduces apoptosis and improves histology in a murine kidney transplant model
Abstract Acute kidney injury (AKI) after transplantation of human deceased donor kidneys is associated with upregulation of tubular toll like receptor 4 (TLR4), but whether TLR4 is required for AKI is unknown. We hypothesized that TLR4 knockout mice (TLR4KO) subjected to cold ischemia followed by ki...
Saved in:
Main Authors: | , , , , |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/6651c1c55f124889a4a21bbb3cb3d3e9 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|