A forward genetic screen identifies Dolk as a regulator of startle magnitude through the potassium channel subunit Kv1.1.

The acoustic startle response is an evolutionarily conserved avoidance behavior. Disruptions in startle behavior, particularly startle magnitude, are a hallmark of several human neurological disorders. While the neural circuitry underlying startle behavior has been studied extensively, the repertoir...

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Autores principales: Joy H Meserve, Jessica C Nelson, Kurt C Marsden, Jerry Hsu, Fabio A Echeverry, Roshan A Jain, Marc A Wolman, Alberto E Pereda, Michael Granato
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/66523a4c7fc74299ad1b74824cdd69a7
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