A Systems Genetics Approach Identified GPD1L and its Molecular Mechanism for Obesity in Human Adipose Tissue

Abstract To explore novel molecular mechanisms underlying obesity, we applied a systems genetics framework to integrate risk genetic loci from the largest body mass index (BMI) genome-wide association studies (GWAS) meta-analysis with mRNA and microRNA profiling in adipose tissue from 200 subjects....

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Bibliographic Details
Main Authors: Hao He, Dianjianyi Sun, Yong Zeng, Ruifeng Wang, Wei Zhu, Shaolong Cao, George A. Bray, Wei Chen, Hui Shen, Frank M. Sacks, Lu Qi, Hong-wen Deng
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/6677ae389d394f33b662b0d26d85f572
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