A mosquito salivary protein promotes flavivirus transmission by activation of autophagy

Mosquito saliva affects transmission of flaviviruses, but underlying mechanisms are incompletely understood. Here, the authors show that Aedes aegypti venom allergen-1 (AaVA-1) promotes dengue and Zika virus transmission by activating autophagy in host immune cells of the monocyte lineage.

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Bibliographic Details
Main Authors: Peng Sun, Kaixiao Nie, Yibin Zhu, Yang Liu, Pa Wu, Ziwen Liu, Senyan Du, Huahao Fan, Chun-Hong Chen, Renli Zhang, Penghua Wang, Gong Cheng
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/6678fcc082af43a2842fd9e6d3502d58
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