A mosquito salivary protein promotes flavivirus transmission by activation of autophagy

Mosquito saliva affects transmission of flaviviruses, but underlying mechanisms are incompletely understood. Here, the authors show that Aedes aegypti venom allergen-1 (AaVA-1) promotes dengue and Zika virus transmission by activating autophagy in host immune cells of the monocyte lineage.

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Autores principales:	Peng Sun, Kaixiao Nie, Yibin Zhu, Yang Liu, Pa Wu, Ziwen Liu, Senyan Du, Huahao Fan, Chun-Hong Chen, Renli Zhang, Penghua Wang, Gong Cheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6678fcc082af43a2842fd9e6d3502d58
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spelling	oai:doaj.org-article:6678fcc082af43a2842fd9e6d3502d582021-12-02T14:41:02ZA mosquito salivary protein promotes flavivirus transmission by activation of autophagy10.1038/s41467-019-14115-z2041-1723https://doaj.org/article/6678fcc082af43a2842fd9e6d3502d582020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14115-zhttps://doaj.org/toc/2041-1723Mosquito saliva affects transmission of flaviviruses, but underlying mechanisms are incompletely understood. Here, the authors show that Aedes aegypti venom allergen-1 (AaVA-1) promotes dengue and Zika virus transmission by activating autophagy in host immune cells of the monocyte lineage.Peng SunKaixiao NieYibin ZhuYang LiuPa WuZiwen LiuSenyan DuHuahao FanChun-Hong ChenRenli ZhangPenghua WangGong ChengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peng Sun Kaixiao Nie Yibin Zhu Yang Liu Pa Wu Ziwen Liu Senyan Du Huahao Fan Chun-Hong Chen Renli Zhang Penghua Wang Gong Cheng A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
description	Mosquito saliva affects transmission of flaviviruses, but underlying mechanisms are incompletely understood. Here, the authors show that Aedes aegypti venom allergen-1 (AaVA-1) promotes dengue and Zika virus transmission by activating autophagy in host immune cells of the monocyte lineage.
format	article
author	Peng Sun Kaixiao Nie Yibin Zhu Yang Liu Pa Wu Ziwen Liu Senyan Du Huahao Fan Chun-Hong Chen Renli Zhang Penghua Wang Gong Cheng
author_facet	Peng Sun Kaixiao Nie Yibin Zhu Yang Liu Pa Wu Ziwen Liu Senyan Du Huahao Fan Chun-Hong Chen Renli Zhang Penghua Wang Gong Cheng
author_sort	Peng Sun
title	A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
title_short	A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
title_full	A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
title_fullStr	A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
title_full_unstemmed	A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
title_sort	mosquito salivary protein promotes flavivirus transmission by activation of autophagy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6678fcc082af43a2842fd9e6d3502d58
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A mosquito salivary protein promotes flavivirus transmission by activation of autophagy

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