Multi-scale inference of genetic trait architecture using biologically annotated neural networks.
In this article, we present Biologically Annotated Neural Networks (BANNs), a nonlinear probabilistic framework for association mapping in genome-wide association (GWA) studies. BANNs are feedforward models with partially connected architectures that are based on biological annotations. This setup y...
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Main Authors: | Pinar Demetci, Wei Cheng, Gregory Darnell, Xiang Zhou, Sohini Ramachandran, Lorin Crawford |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Online Access: | https://doaj.org/article/66812a19d2fa491a9fd1faa01ef7dfef |
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