Requirement of Replication Checkpoint Protein Kinases Mec1/Rad53 for Postreplication Repair in Yeast

ABSTRACT DNA lesions in the template strand block the replication fork. In Saccharomyces cerevisiae, replication through DNA lesions occurs via a Rad6/Rad18-dependent pathway where lesions can be bypassed by the action of translesion synthesis (TLS) DNA polymerases η and ζ or by Rad5-mediated templa...

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Auteurs principaux: Venkateswarlu Gangavarapu, Sergio R. Santa Maria, Satya Prakash, Louise Prakash
Format: article
Langue:EN
Publié: American Society for Microbiology 2011
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Accès en ligne:https://doaj.org/article/66a38f1331a14c769c6d49a653cc48b4
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