Siglec-7 May Limit Natural Killer Cell–mediated Antitumor responses in Bladder Cancer Patients

Siglec-7 May Limit Natural Killer Cell–mediated Antitumor responses in Bladder Cancer Patients

Aberrant glycosylation actively contributes to tumor progression and is a key hallmark of cancer. Most of the glycan moieties expressed on the surface of cancer cells are sialic acids that may modulate antitumor immune responses via binding to sialic acid–binding immunoglobulin-like lectins (Siglecs...

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Détails bibliographiques
Auteurs principaux: Sulayman Benmerzoug, Mathieu F. Chevalier, Laura Villier, Sylvain Nguyen, Valérie Cesson, Anna K. Schneider, Florence Dartiguenave, Sonia-Christina Rodrigues-Dias, Ilaria Lucca, Patrice Jichlinski, Beat Roth, Denise Nardelli-Haefliger, Laurent Derré
Format: article
Langue:EN
Publié: Elsevier 2021
Sujets:
Bladder cancer
Siglec-7
Natural killer cells
Immunoregulation
Immune checkpoint
Diseases of the genitourinary system. Urology
RC870-923
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Accès en ligne:https://doaj.org/article/66cfbf05dc5a4c1abdec773b93fd4a9e
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https://doaj.org/article/66cfbf05dc5a4c1abdec773b93fd4a9e

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