Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation
Abstract Microglia are integral mediators of innate immunity within the mammalian central nervous system. Typical microglial responses are transient, intending to restore homeostasis by orchestrating the removal of pathogens and debris and the regeneration of damaged neurons. However, prolonged and...
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Main Authors: | Erskine Chu, Richelle Mychasiuk, Margaret L. Hibbs, Bridgette D. Semple |
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Format: | article |
Language: | EN |
Published: |
BMC
2021
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Subjects: | |
Online Access: | https://doaj.org/article/66e416b4e60b47ce875018a43baf08b7 |
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