Human nasal challenge with Streptococcus pneumoniae is immunising in the absence of carriage.

Infectious challenge of the human nasal mucosa elicits immune responses that determine the fate of the host-bacterial interaction; leading either to clearance, colonisation and/or disease. Persistent antigenic exposure from pneumococcal colonisation can induce both humoral and cellular defences that...

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Auteurs principaux: Adam K A Wright, Daniela M Ferreira, Jenna F Gritzfeld, Angela D Wright, Kathryn Armitage, Kondwani C Jambo, Emily Bate, Sherouk El Batrawy, Andrea Collins, Stephen B Gordon
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Accès en ligne:https://doaj.org/article/66e905982c694e28a711f28005765625
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